A phase I study of different doses and frequencies of pegylated recombinant human granulocyte-colony

• 作 者: Yan Qin Xiaohong Han Lin Wang
• 机 构: DepartmentofMedicalOncology
• 出 处: 中国癌症研究：英文版
• 发表日期: 2017年5期
• 关键词: RHG-CSF 白血球 殖民地 剂量 化疗 中性 标准 学习 Phase Ⅰ study chemotherapy dose-finding neutropen
• 基金项目: Acknowledgements The authors would like to thank all the investigators and patients who participated in this study. This work was supported by Hangzhou Jiuyuan Gene Engineering Co., Ltd, and partly fu

Objective: The recommended dose of prophylactic pegylated recombinant human granulocyte-colony stimulating factor(PEG rhG-CSF) is 100 μg/kg once per cycle for patients receiving intense-dose chemotherapy.However, few data are available on the proper dose