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目的:观察克咳冲剂治疗小儿喘息性支气管炎的临床疗效。方法:将125例小儿喘息性支气管炎患者随机分为治疗组65例,对照组60例;2组均给予头孢呋辛钠静脉滴注及对症综合治疗,治疗组加用克咳冲剂治疗,对照组加用小儿定喘口服液治疗,比较2组临床疗效。结果:总有效率治疗组90.76%,对照组为86.66%,2组比较,差异无统计学意义(P>0.05)。治疗后治疗组止咳时间、定喘时间均明显短于对照组,差异有统计学意义(P<0.05)。治疗后2组症状体征总积分均较治疗前下降(P<0.05),且治疗组积分下降较对照组更显著(P<0.05)。肺阻抗血流图:治疗后2组波幅(HS)(对照组除外)、右心肌指数(HI)、肺动脉压(PPA)、肺外周阻力(PVR)等指标均较治疗前改善(P<0.05);治疗组HS、PVR改善较对照组更显著(P<0.05)。结论:克咳冲剂治疗小儿喘息性气管炎具有较好的临床疗效。
Objective: To observe the clinical efficacy of Keke Granule in treating infantile asthmatic bronchitis. Methods: A total of 125 children with asthmatic bronchitis were randomly divided into treatment group (n = 65) and control group (n = 60). Both groups were given cefuroxime sodium intravenous drip and symptomatic treatment. The treatment group was treated with Keke granules Group with children Dingchuan oral solution treatment, the clinical efficacy of two groups were compared. Results: The total effective rate was 90.76% in the treatment group and 86.66% in the control group. There was no significant difference between the two groups (P> 0.05). After treatment, the cough time and the time of definite asthma in the treatment group were significantly shorter than those in the control group, the difference was statistically significant (P <0.05). After treatment, the total score of symptoms and signs in the two groups decreased significantly (P <0.05), and the scores of the treatment group decreased more significantly than those in the control group (P <0.05). Pulmonary impedance blood flow diagram: Index of pulmonary arterial pressure (HI), right cardiac index (HI), pulmonary arterial pressure (PPA) and peripheral pulmonary resistance (PVR) ). The improvement of HS and PVR in the treatment group was more significant than that in the control group (P <0.05). Conclusion: Keke granules for treatment of children with asthmatic bronchitis have better clinical efficacy.