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目的观察嗅神经母细胞瘤的临床病理特点。方法经病理学确诊的嗅神经母细胞瘤患者10例,分析患者临床病理特征。结果 10例患者治疗期间死亡2例(20.0%)。按Kadish分期:A期3例,B期5例,C期2例。组织学特征:细胞间可见胞质突起形成的嗜酸性纤维。结论嗅神经母细胞瘤无特殊性,早期诊断难,需要影像学及免疫组化检测的配合,其临床病理特点对诊断及鉴别嗅神经母细胞具有重要意义。
Objective To observe the clinicopathological features of olfactory neuroblastoma. Methods Ten patients with pathologically diagnosed olfactory neuroblastoma were analyzed for clinical and pathological features. Results 10 patients died of treatment in 2 cases (20.0%). According to Kadish staging: A three cases, B five cases, C two cases. Histological features: the formation of cytoplasm can be seen between cells eosinophilic fibers. Conclusion Olfactory neuroblastoma is of no particularity. Early diagnosis is difficult. Imaging and immunohistochemical detection are required. The clinicopathological features of OTC neuroblastoma are important for the diagnosis and differential diagnosis of olfactory neuroblastoma.