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本文对兰州地区258例各型肝炎进行了抗-HCV检测,结果28例阳性,提示本地区肝炎患者中,约10％为丙型肝炎。在既往诊断为非甲非乙型肝炎中,丙型肝炎占1/4以上。28例HCV感染中,14例为单纯感染,11例与HBV重叠感染,2例与HAV重叠感染,1例与HBV及HDV三重感染。重叠感染者病情较重。通过临床分析,HCV感染在重症肝炎中比例最高(26.7％),其次为肝炎后肝硬化(17.0％)和慢性活动性肝炎(15.8％),说明HCV感染与病情加重及肝炎慢性化,纤维化有关。28例丙型肝炎中19例与输血或血制品有关,提示血源传播是HCV的主要感染途径,有必要对献血员进行抗-HCV筛选。
In this paper, 258 cases of hepatitis in Lanzhou were tested for anti-HCV, the results of 28 cases were positive, suggesting that hepatitis patients in the region, about 10% of hepatitis C. In the past diagnosis of non-A non-B hepatitis, hepatitis C accounted for more than 1/4. Of the 28 HCV infections, 14 were exclusively infected, 11 were overlapping with HBV, 2 were overlapping with HAV, and 1 was infected with HBV and HDV. Overlapped patients were in severe condition. Through clinical analysis, HCV infection is the highest among severe hepatitis (26.7%), followed by hepatitis cirrhosis (17.0%) and chronic active hepatitis (15.8%), indicating that HCV infection is aggravated with chronic hepatitis and fibrosis related. Of the 28 cases of hepatitis C, 19 cases were related to transfusions or blood products, suggesting that blood transmission is the major route of HCV infection and it is necessary to screen blood donors for anti-HCV screening.