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对４０例我国北方格林－巴利综合征（ＧＢＳ）患者按１：２配比方法进行了病例对照研究结果发现，腹泻、上呼吸道感染和喷洒有机磷农药是ＧＢＳ的主要环境危险因素，过度疲劳、遭受雨淋是主要的与内环境相关的危险因素；这些因素使罹患ＧＢＳ的危险性增加６倍以上；肝炎，接种脊髓灰质炎、乙脑、麻疹、白百破疫苗和种痘与本病似乎无明显联系。推测ＧＢＳ可能不是单一致病因素，而是由几种独立、不同的致病因素在内环境影响下综合作用的结果。儿童和成人、城市和农村、北方和南方地区居民的致病因素可能有所不同。
A case-control study of 40 patients with GBS in north China according to the 1: 2 ratio method found that diarrhea, upper respiratory tract infection and organophosphate pesticide spraying were the main environmental risk factors of GBS, , Exposure to rain is the main risk factor associated with the environment; these factors increase the risk of developing GBS by more than 6-fold; hepatitis, vaccination with polio, JE, measles, diphtheria and vaccination seem to No obvious connection. Speculated that GBS may not be a single risk factor, but by several independent and different risk factors in the internal environment under the combined effect of the results. The risk factors for residents of children and adults, urban and rural areas, and northern and southern areas may vary.