论文部分内容阅读
检测正常人及口腔颌面部肿瘤患者唾液中癌胚抗原(CEA)和IgA含量,并探讨其临床意义。方法:CEA采用酶联免疫试剂盒,IgA用免疫球蛋白试剂盒(比法法)。结果:恶性肿瘤和正过人比较,CEA和IgA含量都显著增高(P<0.01),恶性肿瘤和良性肿瘤比较,CEA和IgA含量方显著增高(P<0.01)。CEA和IgA含量水平与恶性肿瘤分期呈正相关,CEA相关系往r=0.60(P<0.01),IgA相关系数r=0.41(P<0.05)。结论;口腔便面部恶性肿瘤患者,唾液中CEA、IgA含量显著增高,并与肿瘤分期呈正相关,签提唾液CEA,IgA检测对肿瘤良、恶性鉴别,临床畏助诊断以及恶性肿瘤预后和疗效监测有一定指意义。
To detect saliva CEA and IgA levels in normal human and oral and maxillofacial tumors and to explore its clinical significance. Methods: CEA ELISA kit, IgA immunoglobulin kit (than law). Results: The levels of CEA and IgA in malignant tumors were significantly higher than those in normal controls (P <0.01). The contents of CEA and IgA in malignant tumors were significantly higher than those in benign tumors (P <0.01). The levels of CEA and IgA were positively correlated with the stage of malignant tumor. The correlation coefficient of CEA was r = 0.60 (P <0.01) and IgA was 0.41 (P <0.05). Conclusions: In oral malignancies, CEA and IgA levels in saliva were significantly increased, which were positively correlated with tumor staging. The detection of salivary CEA and IgA in saliva showed good prognosis and malignant prognosis There is a certain meaning.