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目的:研究分析血液置换对危重型AOPP抢救治疗的临床效果.方法:经洗胃后进行血液置换,①扩充血容量,分二路同时尽快输入0.9%生理盐水2000ml.②一次性静脉放血1200～1600ml,废弃.③输入同型新鲜血1200～1600ml.结果:血液置换组32例,治愈31例,占96.88%(31/32),死亡1例,占3.12%(1/32),对照组57例,治愈43例,占75.44%(43/57),死亡14例,占24.56%(14/57).从昏迷、抽搐、迟发性神经反应,胆碱脂酶活力增强等临床资料分析,两组间有显著性差异(P<0.01).结论:血液置换抢救危重型AOPP,危险性极小,能明显增加抢救成功率及减少病死率.
Objective: To study the clinical effect of blood exchange on the rescue and treatment of critical AOPP.Methods: Blood replacement was performed after gastric lavage, (1) the volume of blood was expanded, and 0.9% saline (2000ml) 1600ml, was discarded.③The same type of fresh blood was collected from 1200 to 1600ml.Results: In the blood replacement group, 32 cases were cured, 31 cases were cured, accounting for 96.88% (31/32), 1 died, accounting for 3.12% (1/32) Cases, cured 43 cases, accounting for 75.44% (43/57), 14 cases died, accounting for 24.56% (14/57) .From the coma, convulsions, delayed nerve response, cholinesterase activity and other clinical data analysis, There was a significant difference between the two groups (P <0.01) .Conclusion: Blood replacement to rescue critical AOPP has minimal risk and can significantly increase the success rate of rescue and reduce the mortality.