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目的了解原发性皮肤恶性淋巴瘤（ＰＣＭＬ）的类型分布及临床病理特点。方法主要依据Ｗｉｌｌｅｍｚｅ等１９９４年提出的 ＰＣＭＬ分类标准对 ４２例 ＰＣＭＬ进行分类研究。结果①在 ＰＣＭＬ中，皮肤 Ｔ细胞淋巴瘤（ＣＴＣＬ）多见（６９．０％），其中草样肉芽肿（ＭＦ）占７ ２％。皮肤Ｂ细胞淋巴瘤（ＣＢＣＬ）较少见（３１．０％）。（２）ＰＣＭＬ中男女之比为２：１，中位发病年龄３７岁，ＣＴＣＬ的中位发病年龄小于ＣＢＣＬ（Ｐ＜０．０１），高度恶性ＰＣＭＬ的中位发病年龄小于低度恶性ＰＣＭＬ（Ｐ＜０．０１）。③临床上，ＭＦ可表现为红斑、斑块等非特异性皮损，而其它各类皮损均表现为无症状性皮肤结节、肿块。结论ＰＣＭＬ各类型具有不同的临床病理特点。
Objective To understand the type distribution and clinicopathological features of primary cutaneous malignant lymphoma (PCML). Methods mainly based on Willemze and other PCML classification criteria proposed in 1994 on the classification of 42 cases of PCML. Results ① In PCML, the incidence of cutaneous T-cell lymphoma (CTCL) was more common (69.0%), of which the grass-like granuloma (MF) accounted for 72%. Skin B-cell lymphoma (CBCL) is rare (31.0%). The median age at onset of CTCL was less than that of CBCL (P <0.01). The median age of onset of PCML was lower than that of low-grade PCML P <0.01). ③ clinically, MF can be manifested as erythema, plaque and other non-specific lesions, while all other types of lesions showed asymptomatic skin nodules, lumps. Conclusion All types of PCML have different clinicopathological features.