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用滤纸血片 RIA 筛查了先天性甲功低下症,采集血片11819人,合格血片11092人,采血率占全年出生总数的50%,采血合格率为93.65%。11092人中有10人经两次纸片采血 T_4值均低于正常,又经血清 T4、TSH 检测,加上临床和 X 光检查,确定为先天性甲功低下两例,患病率为1/5500。这说明我市以普及碘盐为主的对碘缺乏症的综合防治措施是十分有效的。本文对9336例统计表明:出生后头半个月 T_4值除第三天偏低外基本平稳,以后随着日龄的增加呈阶梯形上升,并有显著差异。本文对采血、T_4值判定、假阳性、暂时性高 T_4血症,筛查方法与程序进行了讨论。
A filter paper RIA screening of congenital hypothyroidism, blood collection 11819 people, 11092 qualified blood film, blood collection rate accounted for 50% of the total number of births, blood sampling rate of 93.65%. Totally, 1092 out of 11,092 people had T_4 values of blood sampling lower than normal after two times of paper tests, and they were also detected by serum T4 and TSH combined with clinical and X-ray examination. The prevalence of congenital hypothyroidism was 2 / 5500. This shows that the city to promote the iodized salt-based comprehensive prevention and treatment of iodine deficiency disorders is very effective. This article on the 9336 statistics show that: T_4 value in the first half of the birth except for the third day of the low outside the basic stable, with a rise in the later age with a ladder-shaped rise, and significant differences. In this paper, blood sampling, T_4 value judgment, false positive, transient high T_4 hyperlipidemia, screening methods and procedures were discussed.