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心血管疾病的发病机制是复杂的,近年来对前列腺素、血小板在其发病中的作用日趋重视,研究逐步广泛、深入。本文拟从病理生理角度简述前列腺素在心脏血管疾病发病中的作用。一、前列腺素的生成及代谢: 1966年Ambache阐明PG(前列腺素Prostaglandin)类物质是一组20碳不饱和脂肪酸,分子中有一个环戊烷。其主要前体为花生四烯酸(5、8、11、14
The pathogenesis of cardiovascular disease is complex. In recent years, the role of prostaglandin and platelet in their pathogenesis has been paid more and more attention. The research is progressively extensive and in-depth. This article from the pathophysiological point of view prostaglandin in the pathogenesis of cardiovascular disease. First, prostaglandin production and metabolism: In 1966, Ambache clarified PG (Prostaglandin) substances is a group of 20 carbon unsaturated fatty acids, a cyclopentane molecule. Its main precursor is arachidonic acid (5,8,11,14