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目的探讨血必净注射液治疗脓毒血症患者时对凝血功能的影响。方法选取符合入选标准的ICU脓毒症患者42例,分为两组,对照组给予常规综合治疗,治疗组在此基础上加用血必净注射液,分别监测两组患者治疗7d前后PT、APTT、FIB、PLT、D-二聚体。结果治疗后治疗组较常规组PT、APTT时间均有缩短,PLT值增大,D-二聚体下降,FIB变化不大。结论血必净注射液可以改善脓毒症患者的凝血功能,在一定程度上改善预后。
Objective To investigate the effect of Xuebijing injection on coagulation function in patients with sepsis. Methods Forty-two patients with ICU sepsis who met the inclusion criteria were divided into two groups. The control group was given conventional comprehensive treatment. On the basis of this, Xuebijing injection was added to the treatment group to detect PT, APTT, FIB, PLT, D-dimer. Results After treatment, the PT and APTT time of the treatment group was shorter than that of the control group, PLT value increased, D-dimer decreased, but FIB changed little. Conclusion Xuebijing injection can improve the coagulation function in patients with sepsis, to a certain extent, improve the prognosis.