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本文报导3例肝细胞性肝癌引起的淤滞性黄疸,并从病理研究黄疸机制。2例男性均是56岁(例1,2),1例女性15岁(例3)。均因黄疸逐渐加重伴消化道症状入院。除例1有20年大量饮酒史外,余无特殊。体检肝均肿大,右肋缘下3~6厘米,仅例3牌大左肋下4厘米,无腹水征。化验:碱性磷酸酶215~740(正常30~85单位),胆红素总量2.6~39毫克%,直接胆红素2.0~13毫克%,SGOT 110~330单位(正常30~50)。2例化验胆固醇超过350毫克%。全部病例凝血酶元时间正常,HBsAg阴性。例1 拟诊为胆石症、胆总管结石行剖腹探查可见大结节性肝硬化,于总胆管内取出一个3×0.5×0.4厘米硬的有良好结构的胆栓,病理诊为肝源性恶性肿
This article reports three cases of hepatocellular carcinoma caused by stasis jaundice and pathological study of jaundice mechanism. Both men were 56 years old (cases 1 and 2) and 1 female was 15 years old (case 3). Jaundice are gradually aggravated with gastrointestinal symptoms admitted. Except for example 1 has a large number of drinking history of 20 years, I no exception. Physical examination of the liver are swollen, the right costal margin of 3 to 6 cm, only 3 cases left large ribs 4 cm, no signs of ascites. Assay: alkaline phosphatase 215 ~ 740 (normal 30 ~ 85 units), bilirubin total 2.6 ~ 39 mg%, direct bilirubin 2.0 ~ 13 mg%, SGOT 110 ~ 330 units (normal 30 ~ 50). 2 cases of laboratory cholesterol more than 350 mg%. Thrombin time was normal in all cases, with negative HBsAg. Case 1 was diagnosed as cholelithiasis, choledocholithiasis laparotomy can be seen in large nodular cirrhosis in the total bile duct removed a 3 × 0.5 × 0.4 cm hard with good structure of gallbladder, pathological diagnosis of liver-derived malignancy swollen