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研究了不同浓度月桂氮酮对膜-贮库控释型硝酸甘油透过鼠皮的影响;结果表明2%,3%,5%月桂氨酮对于硝酸甘油释放均有明显促进作用,2%为最佳用量;硝酸甘油累积释放量与时间呈良好线性关系,符合零级动力学过程。
The effects of different concentrations of Azone on the release of membrane-depot controlled release nitroglycerin were studied. The results showed that 2%, 3% and 5% laurin could obviously promote the release of nitroglycerin, and 2% The best dosage; the cumulative release of nitroglycerin showed a good linear relationship with time, in line with the zero-order kinetic process.