论文部分内容阅读
我院于1978年8月以吡喹酮治疗日本血吸虫病患者339例,治后7年中共粪便复查7次.于治后1、3个月随访,3例粪孵阳性,累计阴转率为99.2％。治后4年、7年分别粪孵309例及256例,全部阴性:4年及7年酶联免疫吸附试验阴转率分别为84.4％及91.7％。肝肋下及剑突下肿大率治前分别为41.5％及69.6％,治后7年分别下降为14.4％及21.9％,脾肿大治前为32.6％,7年随访时为8％。上述结果证明吡喹酮疗效高,未发现后遗症。
In our hospital, 339 cases of schistosomiasis japonica were treated with praziquantel in August 1978, and 7 cases of post-treatment stool review were performed in 7 years.After 1 and 3 months of follow-up, 3 cases were stool-positive and the cumulative negative conversion rate was 99.2%. After 4 years and 7 years, respectively, 309 and 256 cases of fecal incubation were found, all negative: the negative conversion rates of 84 and 91.7% at 4 years and 7 years respectively. The rates of hepatomegaly and xiphoid edema were 41.5% and 69.6% respectively before treatment and 14.4% and 21.9% respectively after 7 years of treatment, 32.6% before splenomegaly and 8% at 7-year follow-up. The above results show that praziquantel has high curative effect and no sequelae are found.