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目的观察经皮冠状动脉介入治疗(PCI)中血栓抽吸导管联合冠脉内推注替罗非班治疗急性心肌梗死(AMI)的疗效。方法 22例AMI患者行直接PCI术中,应用血栓抽吸导管联合冠脉内推注替罗非班治疗为观察组,以单纯行PCI患者30例作为对照,观察临床疗效。结果观察组在直接支架植入率,血流TIMI分级,无复流或慢血流发生率,术后肌酸激酶同工酶(CK-MB)峰值,ST段回落幅度,左室射血分数(LVEF),左室舒张末期内径(LVEDD)方面优于对照组(P<0.05)。结论 AMI患者应用血栓抽吸导管联合冠脉内推注替罗非班治疗安全有效。
Objective To observe the curative effect of thrombus aspiration catheter combined with intracoronary bolus injection of tirofiban on acute myocardial infarction (AMI) in percutaneous coronary intervention (PCI). Methods Twenty-two patients with AMI underwent direct PCI. Thrombus aspiration catheter and intracoronary bolus of tirofiban were used as the observation group. Thirty patients with simple PCI were used as the control to observe the clinical effect. Results The rate of direct stent implantation, TIMI grade of blood flow, no-reflow or slow blood flow, peak of CK-MB, decrease of ST-segment, left ventricular ejection fraction (LVEF) and left ventricular end-diastolic diameter (LVEDD) were superior to those of the control group (P <0.05). Conclusion Thrombus aspiration catheter combined with intracoronary bolus injection of tirofiban in AMI patients is safe and effective.