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目的探索产前超声诊断胎儿唐氏综合征的临床应用价值,并对此进行评价。方法 862例高危、高龄孕妇作为研究对象,对其进行产前超声常规检查,并在此基础上,利用羊水细胞核型分析对检测结果进行比对。结果 862例高危、高龄孕妇中共有26例唐氏综合征胎儿,占3.02%,同时所有的唐氏综合征的患者在产前均得到确诊,诊断准确率为100%。结论产前超声检查对于发现唐氏综合征的胎儿具有显著的作用,利用羊水细胞核定分析和诊断技术,能够对唐氏综合征的形态结构进行明确的诊断,对于提高其产前诊断率,降低患有染色体缺陷胎儿的出生率具有非常重要的意义,为此在临床医学中值得推广应用。
Objective To explore the clinical value of prenatal ultrasound in the diagnosis of fetal Down Syndrome and to evaluate the value. Methods A total of 862 pregnant women with high risk and advanced age were enrolled in the study. Prenatal ultrasound examination was performed on them. Based on this, prenatal ultrasound was used to compare the results with the karyotype analysis of amniotic fluid cells. Results A total of 26 cases of Down syndrome fetuses were found in 862 high-risk and advanced pregnant women, accounting for 3.02%. All patients with Down’s syndrome were diagnosed prenatally and the diagnostic accuracy was 100%. Conclusion Prenatal ultrasonography has a significant effect on the fetus with Down’s Syndrome. Using amniotic fluid cell nucleus analysis and diagnosis technology can make a clear diagnosis of Down’s syndrome morphological structure, to improve its prenatal diagnosis rate, reduce Birth rate of fetus with chromosomal defect is of great significance, which is worth promoting in clinical medicine.