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研究膀胱全切除术后，继发性尿道肿瘤的发生及对预后的影响。方法：对215例膀胱移行细胞癌行膀胱全切、尿流改道术后，发生继发性尿道癌的16例病人的原发膀胱癌和发生尿道癌的情况进行分析。结果：尿道癌发生率7．4％，膀胱癌累及前列腺是继发尿道癌的危险因素。结论：定期进行残留尿道冲洗脱落细胞学检查是早期发现尿道癌的有效方法，一旦发现应立即施行尿道全切除术。尿道癌的预后不良，多数病人在2年内死亡，应该强调定期检查，以期早期发现，早期治疗，提高生存率。
To study the incidence of secondary urethral tumor and its prognosis after total cystectomy. Methods: A total of 215 cases of bladder transitional cell carcinoma underwent total bladder resection and urinary diversion. The primary bladder cancer and urethral carcinoma of 16 patients with secondary urinary tract cancer were analyzed. Results: The incidence of urethral cancer 7.4%, bladder cancer involving the prostate is a risk factor for secondary urethral cancer. CONCLUSIONS: Periodic residual urethral wash cytology is an effective method for early detection of urethral cancer. Once it is discovered, total urethral resection should be performed immediately. Poor prognosis of urethral cancer, most patients died within 2 years, should be emphasized on a regular basis in order to detect early, early treatment and improve survival.