论文部分内容阅读
当前有关脑缺血损伤后的病理生理一生化的研究至少证实两点。长时间(编者按:一般指20分钟左右)全脑缺血缺氧后,脑仍有可能存活;导致脑死亡的重要原因是脑循环恢复后所产生的一系列继发性病理生理改变。常温下,未用中枢神经系统抑制药,脑循环突然停止10～15秒,脑内可利用氧全部耗尽,病人意识丧失。5分钟后脑内葡萄糖和ATP耗竭。钠泵衰竭和细胞内的高渗透量
Current studies on the pathophysiology of cerebral ischemia after injury at least confirm two points. Long time (Editor’s note: generally refers to 20 minutes or so) global cerebral ischemia and hypoxia, the brain is still likely to survive; lead to brain death is an important reason for the recovery of the cerebral circulation after a series of secondary pathophysiological changes. At room temperature, the central nervous system inhibitors were not used, the brain circulation suddenly stopped 10 to 15 seconds, the brain can be depleted of oxygen available, the patient lost consciousness. After 5 minutes brain glucose and ATP depletion. Sodium pump failure and high intracellular permeability