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人乳头瘤病毒基因分型检测对子宫颈病变的早期发现、宫颈细胞学异常的评估和管理,病程的进展,高度宫颈上皮内瘤变治疗后的随访,以及人群的流行病学状态和病毒疫苗的研制有重要意义.目前国内外对人乳头瘤病毒进行基因分型的方法主要集中在以靶序列扩增为基础的检测和以信号放大为基础的检测技术两方面,本文就这两方面的检测技术加以叙述。
Detection of human papillomavirus genotypes for early detection of cervical lesions, assessment and management of cervical cytology abnormalities, progression of disease, follow-up after treatment of highly cervical intraepithelial neoplasia, and epidemiological status of the population and virus vaccine Of the development of great significance now at home and abroad on the human papillomavirus genotyping methods are mainly focused on target-based amplification and signal amplification based detection of two aspects of this article on these two aspects Detection techniques to be described.