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亨廷顿氏病（Ｈｕｎｔｉｎｇｔｏｎｓ，ｄｉｓｅａｓｅ，ＨＤ）是神经系统一种严重的常染色体显性遗传病［１］。该病的遗传学基因是在ＩＴ１５基因的开放阅读框架的５’端有一个多态的（ＣＡＧ）ｎ三核苷酸重复序列异常扩增，在正常人群中其拷贝数为１１～３４，而ＨＤ...
Huntington’s disease (HD) is a severe autosomal dominant disease of the nervous system [1]. The genetic gene of the disease is an aberrant amplification of a polymorphic (CAG) n trinucleotide repeat at the 5 ’end of the open reading frame of the IT15 gene, with a copy number of 11 to 34 in the normal population HD ...