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对16例肝癌病人外周血及脾静脉血T淋巴细胞亚群检测结果：1）肝癌患者较对照组外周血CD+3、CD+4细胞及CD4／CD8比值降低，CD+8细胞升高。2）肝癌患者脾静脉血较外周血CD+3、CD+4阳性细胞、CD4／CD8比例明显降低，CD+8显著升高。认为随着病程进展，脾脏不但不起正性免疫作用，反而转向负性免疫状态。同时，还对肝癌患者的脾脏手术问题进行了讨论。
The detection results of T lymphocyte subsets in peripheral blood and spleen venous blood of 16 patients with hepatocellular carcinoma were as follows: 1) The ratios of CD+3, CD+4 cells and CD4/CD8 in peripheral blood of patients with liver cancer were lower than those in control group, and CD+8 cells were elevated. 2) The proportion of CD+3, CD+4 positive cells, and CD4/CD8 ratio in peripheral blood of patients with hepatocellular carcinoma were significantly lower than those in peripheral blood, and CD+8 was significantly increased. It is believed that as the course of the disease progresses, the spleen not only fails to have a positive immune function but turns to a negative immune state. At the same time, the issue of splenic surgery for liver cancer patients was also discussed.