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采用酶免疫测定法(EIA)测定17例小儿肾外症状性肾炎(肾外肾炎)的尿微量转铁蛋白(TRF)含量并探讨其临床意义。结果在尿常规未出现改变前尿TRF水平即明显增高(P<0.01),其增高水平与典型的链球菌感染后急性肾小球肾炎(链感肾炎)极度相似(P>0.05)。尿TRF升高可作为肾小球损害的早期判断指标,对早期临床诊断较困难的肾外肾炎具有较好的诊断价值。
Enzyme immunoassay (EIA) was used to determine urinary microtransferrin (TRF) levels in 17 children with extrarenal nephritic nephritis (nephritis) and its clinical significance. Results Urinary TRF level was significantly increased before urinary routine change (P <0.01). The level of TRF was extremely similar to that of typical acute glomerulonephritis (streptococcal nephritis) after streptococcal infection (P> 0.05). Increased urine TRF can be used as an early indicator of glomerular damage, early clinical diagnosis of extra renal nephritis has a better diagnostic value.