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不稳定型心绞痛是一种急性心肌缺血状态,易发展为急性心肌梗死或猝死。其发病机制主要是因为冠状动脉粥样硬化斑块破裂,形成血栓,造成管腔的不完全狭窄及远端小动脉栓塞,是冠心病常见类型。目前调脂药物有很多,传统常规药物治疗一般给予硝酸脂类、B受体阻滞剂、钙拮抗剂、阿司匹林等;心血管事件发生率比较高,约10-20%。他汀类药物能稳定动脉粥样硬化斑块,降低心血管事件的发生率。我院2004年1月—2007年1月对80例不稳定性心绞痛患者给予辛伐他汀药物治疗,疗效满意,现报告如下。
Unstable angina is an acute myocardial ischemic condition that is predisposed to developing acute myocardial infarction or sudden death. Its pathogenesis is mainly due to coronary atherosclerotic plaque rupture, thrombosis, resulting in incomplete lumen and distal arteriole embolism, is a common type of coronary heart disease. Currently there are many lipid-lowering drugs, conventional conventional drug treatment given nitrates, B receptor blockers, calcium antagonists, aspirin, etc .; cardiovascular events were relatively high, about 10-20%. Statins stabilize atherosclerotic plaques and reduce the incidence of cardiovascular events. In our hospital from January 2004 to January 2007 80 patients with unstable angina were given simvastatin drug treatment, with satisfactory results, are as follows.