论文部分内容阅读
为阻止角膜新生血管,改善角膜移植片的预后,用同种异体角膜缘上皮移植联合角膜移植术,对陈旧性眼化学烧伤53例(53眼),作干燥全角膜板层移植组(21眼),和穿透性角膜移植组(10眼)联合角膜缘上皮移植。以及对照组——单纯作全角膜板层移植组(22眼)进行观察分析。结果:联合干燥全角膜板层移植者中,角膜上皮愈合时间为4~14天,平均7.4天。4眼发生排斥反应。15眼角膜上皮一直较稳定。植片保持透明者15眼71.4%。穿透性角膜移植组上皮愈合时间为3~5天,平均4天,9眼角膜上皮保持稳定。两组均有70%的病例较有效地阻止角膜新生血管与假性胬肉的发生。对照组愈合时间为7~20天,平均13.7天。22例中9只眼(40.9%)发生上皮早期剥脱或持续上皮缺损。结论:对严重的眼部化学伤施行角膜缘上皮移植联合角膜移植是较有效的治疗方法。
In order to prevent corneal neovascularization and improve the prognosis of corneal allograft, corneal limbal epithelial allograft combined with corneal transplantation was performed in 53 cases (53 eyes) ), And penetrating keratoplasty (10 eyes) combined with limbal epithelial transplantation. And the control group - simply as a whole corneal flap transplantation group (22 eyes) were observed and analyzed. Results: The corneal epithelial healing time was 4 to 14 days in the combined dry corneal graft, with an average of 7.4 days. 4 cases of rejection occurred. 15 corneal epithelial has been more stable. 15 cases of grafts remained transparent 71.4%. The penetrating keratoplasty group epithelial healing time was 3 to 5 days, an average of 4 days, 9 corneal epithelial cells remained stable. 70% of the cases in both groups were more effective in preventing the occurrence of corneal neovascularization and false pterygium. Control group healing time was 7 to 20 days, an average of 13.7 days. Nine of 22 eyes (40.9%) developed early epithelial exfoliation or persistent epithelial defects. Conclusion: Corneal limbal epithelial transplantation combined with corneal transplantation is a more effective treatment for severe chemical eye injury.