Identification of long non-coding RNA p34822 as a potential plasma biomarker for the diagnosis of he

• 作 者: Cheng Wang Tianyu Ren Keyu Wang Shaogeng Zhang Shubin Liu Hu Chen Penghui Yang
• 机 构: The 307 Hospital OfPLA,The 302 Hospital OfPLA,Beijing Institute of Microbiology and Epidemiology,Sta
• 出 处: Science China(Life Sciences)
• 发表日期: 2017年09期
• 关键词: fetoprotein biomarker vital deaths managing mortality specificity diagnostic ope

Dear Editor,Hepatocellular carcinoma(HCC)is the third leading cause of cancer-related deaths worldwide(Li and Satomura,2015).Early diagnosis and treatment are vital for reducing mortality.Currently,biomarkers such as serum alpha fetoprotein(AFP),AFP-L2,and carcinoembryonic antigen are widely used tumor markers for managing HCC in patients(Shi et al.,2016).However,because of their low diagnostic sensitivity and specificity,novel biomarkers with high sensitivity and specificity for early HCC diagnosis are needed.