慢性活动性肝炎

• 作 者: 孟宪益
• 出 处: 国外医学参考资料.流行病学传染病学分册
• 发表日期: 1975年03期
• 关键词: 慢性活动性肝炎 肝脏疾病 慢性活动性 自身免疫反应 致病性 肝细胞损害 抗体 血清 慢性迁延性肝炎 细胞免疫

Reed等1973年报道,英国 17％慢性活动性肝炎病人HBAg阳性,其免疫反应是产生肝细胞损害的原因。其它的一些研究认为自身免疫反应是经常存在的,其中一些可能有致病性。在血清中常有抗核、抗线粒体和抗平滑肌的抗体,但并不是器官所特有的,因此这些抗体似乎不是肝脏疾病的发病原因。最近发现在慢性活动性肝

Reed and other reports in 1973 reported that 17% of UK patients with chronic active hepatitis HBAg positive immune response is the cause of liver cell damage. Other studies suggest autoimmune reactions are frequent, some of which may be pathogenic. Antibodies, which are anti-nuclear, anti-mitochondrial and anti-smooth muscle, are often found in serum but are not organ-specific and therefore do not appear to be responsible for the pathogenesis of liver disease. Recently found in chronic active liver