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第一次全国临床神经生化会议于1986年5月19～21日在天津召开。兹将会议主要内容简介如下: 一、脑血病疾病方面(一)重医大报告了脑血管病脑脊液中前列腺素(PG)分组的观察(25例)。PGF_(2α)为人体中枢神经系统(CNS)主要前列腺素之一,具有收缩血管和致血小板聚集的作用,对神经元的体液介导和刺激调节有独特作用。正常CNS合成量甚微,脑血管病时合成与释放剧增,能引起脑血管痉挛,促进脑水肿。他们发现不同脑血管病的PGF_(2α)含量不同,出血型较梗阻CSF型含量早且高,提示早期可用前列腺素抑制剂防治脑血管病。而后期含量与病情转归有关。对照组早期CSF PGF_(2α)含量为281±29pg/ml。
The first national meeting of clinical neurobiology was held in Tianjin from May 19 to May 21, 1986. The main contents of the meeting are summarized as follows: 1. Cerebrovascular Diseases (1) We have reported the observation of PG group in cerebrovascular disease (25 cases). PGF_ (2α) is one of the main prostaglandins in human central nervous system (CNS). It has the function of constricting blood vessels and causing platelet aggregation, and plays a unique role in humoral mediation and stimulation regulation of neurons. The amount of normal synthesis of CNS is very small, synthetic and release of cerebrovascular disease can cause cerebral vasospasm and promote cerebral edema. They found that different cerebrovascular disease PGF_ (2α) content is different, type of bleeding more obstructive CSF content early and higher, suggesting that early available prostaglandin inhibitors prevent and treat cerebrovascular disease. The late content and prognosis of the disease. The early CSF PGF 2α content in the control group was 281 ± 29 pg / ml.