小儿科的非酒精的脂肪肝疾病: 新卓见和未来方向

• 作 者: Pierluigi Marzuillo Emanuele M
• 机 构: DepartmentofwomenandchildrenandGeneralandSpecializedSurgery,DepartmentofPediatrics
• 出 处: 世界肝病学杂志：英文版（电子版）
• 发表日期: 2014年4期
• 关键词: Non ALCOHOLIC FATTY liver disease PNPLA3 Obesity Insulin resistance GLUCOKINASE
• 基金项目: Supported by The American Heart Association(AHA),No.13SDG14640038,2012 Yale Center for Clinical Investigation(YCCI)scholar award to Santoro N,CTSA Grant Number UL1 RR024139 from the National Center fo

One of the most common complications of childhood obesity is the non-alcoholic fatty liver disease(NAFLD),which is the most common form of liver disease in children.NAFLD is defined by hepatic fat infiltration 】 5% hepatocytes,as assessed by liver biopsy,