Potential role of NADPH oxidase in pathogenesis of pancreatitis

• 作 者: Wei-Li Cao Xiao-Hui Xiang Kai
• 机 构: DepartmentofHepatopancreatobiliaryandSplenicMedicine
• 出 处: 世界胃肠病理生理学杂志：英文版（电子版）
• 发表日期: 2014年3期
• 关键词: NICOTINAMIDE ADENINE DINUCLEOTIDE phosphate oxidase Reactive oxygen species PANC
• 基金项目: Supported by The National Natural Science Foundation of China,No.81173393,the Natural Science Foundation of Tianjin City,No.12YFJZJC00800,the Scientific Research Foundation(No.WHM201222,FYM201114),the

Studies have demonstrated that reactive oxygen species(ROS) are closely related to inflammatory disorders. Nicotinamide adenine dinucleotide phosphate oxidase(NOX), originally found in phagocytes, is the main source of ROS in nonphagocytic cells. Besides