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目的:分析研究胃上部癌采取全胃切除术与近端胃切除术治疗的临床效果。方法:抽取2011年1月-2014年1月在我院收治的患有胃上部癌的病人100例,采取随机抽取模式,随机分为两组,每组各50例。对照组对病人采取近端胃部切除手术给予治疗,实验组对病人采取全胃切除手术给予治疗,对两组临床治疗和并发症给予对比分析。结果:两组临床手术以后7天体质量下降情况差异不具有统计学意义(P<0.05);对照组血红蛋白以及血清白蛋白水平全部高于实验组,两组间差异具有统计学意义(P<0.05);实验组并发症发生率12%,对照组并发症发生率22%,实验组并发症发生率明显低于对照组,两组间差异具有统计学意义(P<0.05);实验组其1年和3年生存率为92%和64%;对照组其1年和3年生存率为94%和62%,两组病人远期生存情况差异不具有统计学意义(P<0.05)。结论:胃上部癌采取全胃切除术和近端切除手术都可以获得良好的治疗效果,可是全胃切除术并发症发生率较少,具有临床推广价值。
Objective: To analyze the clinical effect of total gastrectomy and proximal gastrectomy in the treatment of upper gastric cancer. Methods: A total of 100 patients with upper gastric cancer who were admitted to our hospital from January 2011 to January 2014 were selected and randomly divided into two groups (50 in each group). In the control group, proximal gastric resection was performed on the patients. In the experimental group, total gastrectomy was performed on the patients, and the clinical treatment and complications of the two groups were compared and analyzed. Results: There was no significant difference in the body weight loss between the two groups 7 days after operation (P <0.05). The levels of hemoglobin and serum albumin in the control group were all significantly higher than those in the experimental group (P <0.05) ). The incidence of complications in the experimental group was 12%, the incidence of complications in the control group was 22%, the incidence of complications in the experimental group was significantly lower than that in the control group, the difference was statistically significant (P <0.05) Year and 3-year survival rates were 92% and 64% respectively. The 1-year and 3-year survival rates were 94% and 62% in the control group, respectively. There was no significant difference in long-term survival between the two groups (P <0.05). Conclusion: Total gastrectomy and proximal resection surgery can achieve good therapeutic effect, but the incidence of total gastrectomy complications is less, with clinical value.