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目的：观察榄香烯加顺铂与单用顺铂胸腔内注药治疗癌性胸腔积液的疗效。方法：把确诊为癌性胸腔积液患者随机分为两组：治疗组应用榄香烯乳２００～３００ｍｇ加顺铂４０ｍｇ，对照组用顺铂６０～８０ｍｇ，于确诊后１周（中位数）行胸腔套管插管法闭式引流后注入上述药物治疗。结果：治疗组完全缓解１１例占６５％、部分缓解５例占２９％、无效１例占６％、有效率９４％；对照组则完全缓解为５例占２９％、部分缓解１０例占５９％、无效２例占１２％，有效率８８％。两组完全缓解有显著性差异（χ２＝３．８８，Ｐ＜０．０５），治疗组优于对照组，而总有效率无显著性差异。不良反应治疗组似少于对照组。结论：用榄香烯加顺铂治疗癌性胸腔积液疗效较单用顺铂者好。
OBJECTIVE: To observe the therapeutic effect of elemene plus cisplatin and cisplatin intrathoracic injection for cancerous pleural effusion. Methods: Patients diagnosed with cancerous pleural effusion were randomly divided into two groups: the treatment group was treated with elemene milk 200-300mg plus cisplatin 40mg, and the control group was treated with cisplatin 60-80mg, 1 week after diagnosis (median ) After the closed drainage of the thoracic cannula intubation method, the above-mentioned drugs were injected. Results: In the treatment group, 11 cases accounted for 65% complete remission, partial remission 5 cases accounted for 29%, invalid 1 case 6%, and effective rate 94%; in the control group, 5 cases accounted for 29% complete remission, partial remission 10 cases accounted for 59 %, invalid 2 cases accounted for 12%, efficiency 88%. There was a significant difference in complete remission between the two groups (χ2=3.88, P<0.05). The treatment group was superior to the control group, and there was no significant difference in the total effective rate. The adverse reaction treatment group appeared to be less than the control group. Conclusion: The efficacy of elemene plus cisplatin in the treatment of cancerous pleural effusion is better than that of cisplatin alone.