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目的:观察自拟健脾化癥汤联合替加氟化疗对晚期胃癌的临床疗效。方法:将60例患者随机分为2组各30例,对照组予替加氟片口服治疗,连服28天为1周期,休息14天继续下1周期治疗,治疗4周期评价疗效。治疗组在对照组治疗的基础上予健脾化癥汤治疗,每天1剂,水煎服,疗程同对照组。比较2组肿瘤病灶大小、生活质量及中医证候情况。结果:2组肿瘤病灶大小比较,差异无显著性意义(P>0.05);治疗组在改善生活质量及中医证候方面均明显优于对照组,差异均有显著性意义(P<0.05)。结论:健脾化癥汤联合替加氟化疗在提高患者生活质量和改善中医证候方面取得较好的疗效。
Objective: To observe the clinical efficacy of self-made Jianpi Huayu Decoction combined with tegafur chemotherapy for advanced gastric cancer. Methods: Sixty patients were randomly divided into two groups of 30 cases. The control group was treated with oral fluoridation tablets orally, even for 28 days for one cycle. The rest for 14 days was continued for one cycle, and the treatment for 4 cycles was evaluated. The treatment group was given Jianpi Huayu Decoction on the basis of the treatment of the control group, one day, Shuijianbi, treatment with the control group. The tumor size, quality of life and TCM syndromes were compared between the two groups. Results: There was no significant difference in tumor size between the two groups (P> 0.05). The treatment group was significantly better than the control group in improving quality of life and TCM syndromes (P <0.05). Conclusion: Jianpi Huayu Decoction combined with tegafur chemotherapy has good curative effect in improving the quality of life of patients and improving TCM syndromes.