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目的通过研究无锡市无偿献血人群HIV感染确证者的失访情况,根据失访者的流行病学特征制定有效的防治措施,降低经血传播疾病的发生,提高血液安全。方法用2种不同厂家的酶联免疫吸附试验试剂对无偿献血者的血液标本进行抗-HIV检测,结果检测阳性者送至无锡市疾控中心用蛋白免疫印迹法确证。统计HIV感染确证阳性率并收集感染者流行病学资料进行分析。结果自2011年至2015年无锡市无偿献血人群HIV的感染确证率为1万分之2.41(54/224 110),呈逐年上升趋势;在54例HIV感染者中,失访13例((24.1%),失访率逐年增加(P=0.012),2015年的失访者是过去四年的总和。失访者在已婚人群(45%)中高于未婚(14.8%)和离异人群(0%)(P=0.005)。结论本地区无偿献血人群中HIV感染者失访率较高,已婚感染者的失访率高于未婚和离异者;此类人员利用献血的方式检测是否感染HIV,增加了采供血过程中的风险。采供血机构应加大献血征询力度,合理引导此类人员到疾控部门检测,降低HIV感染者的失访率,保证血液安全。
Objective To study the loss-of-HIV status of HIV-positive people in Wuxi voluntary blood donation population and to establish effective prevention and control measures based on the epidemiological characteristics of those lost to reduce the incidence of blood-borne diseases and improve blood safety. Methods Anti-HIV was detected in blood samples from two blood donors with two different kinds of ELISA reagents. The positive samples were sent to Wuxi CDC for confirmation by Western blotting. The positive rate of HIV infection was confirmed and the epidemiological data of infected persons were collected for analysis. Results HIV infection confirmed in Wuxi non-compensatory blood donors from 2011 to 2015 was 2.41 (54/224 110), showing an increasing trend year by year. Of the 54 HIV-infected patients, 13 (24.1% ), And the rate of loss of follow-up increased year by year (P = 0.012), and the number of those who lost their jobs in 2015 was the sum of the past four years.Fifty-year-olds were higher than married women (14.8%) and divorced people (0% ) (P = 0.005) .Conclusion The rate of loss of HIV-infected persons in unpaid blood donation population in this area is higher than that of unmarried and divorced people in married patients. Such persons use blood donation to detect whether they are infected with HIV, Increase the risk in the process of blood collection and blood collection and blood donation agencies should increase the efforts to seek blood donation, and reasonable guidance of such personnel to the disease control department testing, reduce the rate of loss of HIV infection, to ensure blood safety.