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目的比较18F-脱氧葡萄糖(FDG)PET/CT与磁共振成像(MRI)对肺癌脊椎转移临床诊断价值的差异。方法 35例肺癌患者同时行18F-FDG PET/CT及MRI检查,比较两种方法诊断脊椎转移病灶的敏感性和特异性。统计学方法采用配对四格表资料c2检验,P<0.05被认为差异有统计学意义。结果经病理或随访确诊脊椎转移患者27例。以受累椎体病灶个数为统计单位,脊椎范围内共875个椎体,158个为真阳性,717个为真阴性。PET/CT诊断正确148个病灶,假阴性10个,假阳性24个,其敏感性93.6﹪,特异性96.8﹪。MRI诊断正确150个病灶,假阴性8个,无假阳性,其敏感性94.9﹪,特异性100﹪。结论对肺癌脊椎骨转移的诊断,MRI较PET/CT具有更高的敏感性、特异性。
Objective To compare the clinical diagnostic value of 18F-FDG PET / CT and magnetic resonance imaging (MRI) in patients with spine metastasis of lung cancer. Methods Twenty-five patients with lung cancer underwent both 18F-FDG PET / CT and MRI examinations. The sensitivity and specificity of the two methods for the diagnosis of spinal metastases were compared. Statistical methods using paired four grid data c2 test, P <0.05 was considered statistically significant. Results Twenty-seven patients with spondylolisthesis were confirmed by pathology or follow-up. To the number of vertebral lesions involved as a statistical unit, a total of 875 vertebra vertebrae, 158 were true positive, 717 true negative. PET / CT diagnosis of the correct 148 lesions, false negative 10, 24 false positives, the sensitivity of 93.6%, a specificity of 96.8%. MRI diagnosis of 150 lesions, false negative 8, no false positive, the sensitivity of 94.9%, 100% specificity. Conclusions MRI is more sensitive and specific than PET / CT in diagnosing lung spine metastasis.