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【目的】探讨应用开塞露和金双歧对早产儿早期胆红素水平的影响。【方法】将82例早产儿随机分为观察组(42例)和对照组(40例),对观察组42例早产儿生后30 min内、生后12~24 h和24~48 h时间段中各使用开塞露注肛1次,每次5 mL,保留1~2 min;金双歧生后当天开始使用,每次1/2片,每日3次,连用3 d。比较两组在生后24、48、72、96、120、144 h和168 h血清胆红素水平和高胆红素血症的发生率。【结果】观察组血清胆红素浓度均低于对照组,且观察高胆红素血症的发生率(14.3%)显著低于对照组(45.0%)(χ2=9.336,P<0.01)。【结论】早产儿早期应用开塞露和金双歧,可有效抑制其血清胆红素水平,减少高胆红素血症的发生。
【Objective】 To explore the effect of Kaixailu and Jinshuangqi on the early bilirubin level in preterm infants. 【Methods】 Eighty-two premature infants were randomly divided into observation group (n = 42) and control group (n = 40). 42 cases of preterm infants in observation group within 30 min after birth, 12 to 24 h and 24 to 48 h after birth Sections of the use of the open plug exposed anal 1 times, each 5 mL, retained 1 ~ 2 min; gold bifid on the day after birth began to use, each 1/2 tablets, 3 times daily, once every 3 d. The incidences of serum bilirubin and hyperbilirubinemia at 24, 48, 72, 96, 120, 144 h and 168 h after birth were compared between the two groups. 【Results】 The serum bilirubin concentration in the observation group was lower than that in the control group. The incidence of hyperbilirubinemia (14.3%) was significantly lower than that of the control group (45.0%) (χ2 = 9.336, P <0.01). 【Conclusion】 The early application of Kaiser and Jinshuangqi can effectively inhibit the serum bilirubin levels and reduce the incidence of hyperbilirubinemia.