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目的评价长江流域6城市2005―2007年抗真菌药物利用情况。方法收集长江流域6城市157家医院2005―2007年抗真菌药物应用数据,进行金额及用药频度(DDDs)统计分析,对用药金额和DDDs进行排序。结果2005―2007年6城市抗真菌药物用药总金额有所增加,三唑类增幅最大,棘白菌素类增长率最高。金额前2位是氟康唑与伊曲康唑,DDDs前2位是伊曲康唑与特比萘芬;进口药及合资药占据70%以上市场,国产药比例逐年下降。结论2005―2007年长江流域6城市抗真菌药物用药金额呈增长趋势,三唑类增长最明显。
Objective To evaluate the use of antifungal drugs in six cities in the Yangtze River valley from 2005 to 2007. Methods The data of antifungal drug use in 157 hospitals in 6 cities of 6 cities in the Yangtze River Basin during 2005-2007 were collected and statistically analyzed for the amount of DDDs and DDDs. Results The total amount of antifungal drugs in 6 cities increased from 2005 to 2007, with the highest increase in triazoles and the highest increase in echinocandins. The top two are fluconazole and itraconazole, the first two DDDs are itraconazole and terbinafine; imported drugs and joint-stock drugs account for more than 70% of the market, the proportion of Chinese-made drugs declines year by year. Conclusions The amount of antifungal drugs in six cities in the Yangtze River valley increased with the increase of triazoles in 2005-2007.