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目的:分析小儿慢性胃炎患儿内镜检查与病理组织学改变的相关性。方法:研究对象为本院自2010年3月至2013年3月收治的186例慢性胃炎儿童,均接受胃镜和病理学两种方式诊断,评价并分析镜下表现与病理学相关性。结果:经胃镜诊断结果为178例慢性浅表性胃炎(CSG),8例慢性萎缩性胃炎(CAG)。病理学诊断结果为170例CSG,10例CAG,6例胃黏膜无损害。胃镜与病理学诊断CSG的准确度为90.32%,胃镜与病理学诊断CAG的准确度为93.54%。对CSG的阳性预测值中,红白间隔、红色居多及充血水肿占92.42%和92.96%。病理组织学性的溃烂、活动性炎症、肠上皮化生与胃镜下各种表现的关系均不够密切。胃镜与病理学诊断CSG和CAG的灵敏度分别为97.06%和30.00%,差异具有显著性(P<0.05)。结论:儿童CSG镜下主要形态对病理诊断CSG的灵敏性好且有相关性,而胃镜诊断CAG对病理诊断CAG的灵敏性差。
Objective: To analyze the correlation between endoscopy and histopathological changes in children with chronic gastritis. Methods: A total of 186 children with chronic gastritis treated in our hospital from March 2010 to March 2013 were diagnosed by gastroscopy and pathology. The correlation between microscopic findings and pathology was evaluated and analyzed. Results: The results of gastroscopy were 178 cases of chronic superficial gastritis (CSG) and 8 cases of chronic atrophic gastritis (CAG). Pathological diagnosis of 170 cases of CSG, 10 cases of CAG, 6 cases of gastric mucosa without damage. Gastroscopy and pathology diagnosis of CSG accuracy was 90.32%, endoscopy and pathology diagnosis of CAG accuracy was 93.54%. The positive predictive value of CSG, red and white interval, the majority of red and congestion congestion accounted for 92.42% and 92.96%. Histopathologic ulceration, active inflammation, intestinal metaplasia and endoscopic various manifestations of the relationship are not close enough. Gastroscopy and pathological diagnosis of CSG and CAG sensitivity were 97.06% and 30.00%, the difference was significant (P <0.05). Conclusion: The main morphological features of CSG in children are good and sensitive to the pathological diagnosis of CSG, while the diagnosis of CAG by endoscopy is poorly sensitive to the diagnosis of CAG.