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抗聚集剂及血管扩张剂前列腺素(PGI_2)在母及胎儿血管中的缺少,可能涉及预痫的形成问题,因为这现象可能导致胎儿胎盘单位血流减少,引起宫内生长迟缓和其他的合并症。有报道非毒性胎盘功能不足患者 PGI_2的产生也缺少,这就更引起大家考虑 PGI_2缺乏可能与预痫病因有关。但是,是否PGI_2缺少与分娩方式有关?这些患者往往是剖腹分娩或引产,且常应用全麻或硬膜外麻醉。因此本文观察分娩方式及母体麻醉后对脐 PGI_2产生的影响,以及预痫、原发性高血压及特发性宫内生长迟缓对脐 PGI_2的影响。本文观察71例不吸烟、于孕36-41周分娩的产妇。9例为急性预痫、7例胎儿宫内生长迟缓、9例原发性高血压和46例正常孕妇作对照。71侧中阴逍分娩者48例:25例自娩、23例引产。23例选择性剖腹产中15例硬膜外麻醉、8例全身麻醉。4例婴
The lack of PGI2 in maternal and fetal blood vessels may be related to the formation of pre-eclampsia as this phenomenon may lead to decreased blood flow to the fetal placenta, resulting in intrauterine growth retardation and other complications disease. It has been reported in patients with non-toxic placental insufficiency PGI_2 production is also lacking, which led to further consideration that PGI_2 deficiency may be associated with preeclampsia. However, is there a lack of PGI 2 associated with mode of delivery? These patients are often delivered by cesarean section or abortion, and general anesthesia or epidural anesthesia is often used. Therefore, this article observed the mode of delivery and maternal anesthesia on umbilical PGI_2 production, as well as pre-eclampsia, essential hypertension and idiopathic intrauterine growth retardation of umbilical PGI_2. This article observed 71 cases of non-smoking, pregnant 36-41 weeks of delivery of mothers. 9 cases were acute preeclampsia, 7 cases of intrauterine growth retardation, 9 cases of essential hypertension and 46 normal pregnant women as controls. 71 side of the Yin Xiao delivery 48 cases: 25 cases of childbirth, 23 cases of induced labor. Fifteen of 23 patients undergoing selective caesarean section received epidural anesthesia and 8 received general anesthesia. 4 cases of infants