长期使用喹硫平致性功能障碍率较低

• 作 者: 李瑛
• 出 处: 中国药师
• 发表日期: 2007年08期
• 关键词: 性功能障碍 喹硫平 精神分裂症 观察终点 精神病 精神障碍 调查表 抗精神病药 基线 平对

在患有精神分裂症或精神分裂症样精神障碍的门诊患者中进行一个多中心,非比较的公开标签试验,目的是评估长期使用喹硫平对这类患者性功能的影响。试验共纳入86例患者,其中82例进入意向治疗(iment to treat)样本。精神病相关的性功能障碍调查表总体记分从基线至试验观察终点呈进行性和显著性下降。进行意向治疗分析的患者中,仅

A multicenter, non-comparative, open-label, open-label trial of outpatients with schizophrenia or schizophreniform psychosis was conducted to assess the effect of long-term use of quetiapine on sexual function in these patients. A total of 86 patients were included in the trial, 82 of whom were enrolled in a iment to treat sample. The overall score for the psychiatric-related sexual dysfunction questionnaire was statistically and significantly decreased from baseline to the end of the trial. Only patients who performed intention-to-treat analyzes