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探讨18F-脱氧葡萄糖(18F-FDG) PET/CT显像对结直肠癌术后复发和转移的诊断价值。对63例结直肠癌术后患者进行全身18F-FDG PET/CT显像检查。根据手术或活组织病理学检查、多种影像学检查及6个月以上的临床随访结果。63例患者中,有45例最终诊断为肿瘤复发或转移。以患者计算,18F-FDG PET/CT显像诊断的灵敏度为95.6%,特异性为83.3%,准确性为92.1%。以病灶计算,18F-FDG PET/CT显像诊断的灵敏度为96.9%,特异性为66.7%,准确性为95.7%。18F-FDG PET比同机CT平扫对病灶检出率高(χ2=6.449,P=0.011)。依据18F-FDG PET/CT显像结果,13例(20.6%)患者改变了临床再分期,其中12例提高了临床再分期、1例降低了临床再分期。18F-FDG PET/CT显像对结直肠癌术后复发和转移的诊断具有重要临床价值。
To investigate the diagnostic value of 18F-FDG PET / CT in the diagnosis of postoperative recurrence and metastasis of colorectal cancer. Sixty-three patients with postoperative colorectal cancer underwent whole-body 18F-FDG PET / CT imaging. According to surgical or biopsy, a variety of imaging studies and clinical follow-up results of more than 6 months. Of the 63 patients, 45 were finally diagnosed as tumor recurrence or metastasis. In patients, 18F-FDG PET / CT imaging showed a sensitivity of 95.6%, specificity of 83.3% and accuracy of 92.1%. The lesion calculation, 18F-FDG PET / CT imaging diagnostic sensitivity was 96.9%, specificity was 66.7%, accuracy of 95.7%. The detection rate of 18F-FDG PET was higher than that of CT (χ2 = 6.449, P = 0.011). According to 18F-FDG PET / CT imaging findings, 13 patients (20.6%) changed clinical re-staging, of whom 12 improved clinical re-staging and 1 reduced clinical re-staging. 18F-FDG PET / CT imaging of colorectal cancer recurrence and metastasis of diagnosis has important clinical value.