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目的探讨胃癌前病变的转归以及与胃癌的关系。方法收集分析 1988～ 1997年我院经胃镜及病理确诊的胃癌前病变患者 500例相关资料，进行 5～ 10年的胃镜跟踪随访。结果 (1)胃溃疡组 (GU)156例，经治疗总有效率为 84.6％，发生癌变 4例，检出率为 2.6％； (2)慢性萎缩性胃炎组 (CAG)300例，经治疗后，好转 98例，占 32.6％，无变化 131例，占 43.7％，不同程度加重 71例，占 23.7％，发生癌变 6例，检出率为 2％； (3)胃息肉组 44例，其中 2例为多发性息肉，均发生癌变，占 4.5％。结论确认为胃癌前病变的患者应积极治疗，可提高治愈率，但因种种原因，部分患者可加重，少数可癌变。因此采取长期胃镜跟踪随访是必要的、有效的措施。
Objective To investigate the prognosis of gastric precancerous lesions and their relationship with gastric cancer. Methods We collected and analyzed 500 cases of gastric precancerous lesions diagnosed by gastroscopy and pathology in our hospital from 1988 to 1997 and followed up for 5 to 10 years by gastroscopy. Results (1) Gastric ulcer group (GU) 156 cases, the total effective rate was 84.6% after treatment, 4 cases had carcinogenesis, the detection rate was 2.6%; (2) 300 cases of chronic atrophic gastritis (CAG), treated After that, 98 cases were improved, accounting for 32.6%, 131 cases were unchanged, accounting for 43.7%, 71 cases were differently aggravated, accounting for 23.7%, 6 cases were cancerous, and the detection rate was 2%; (3) 44 cases of gastric polyps group, Two of them were polyps, all of which were cancerous, accounting for 4.5%. Conclusion Patients with precancerous lesions should be actively treated and the cure rate can be improved. However, due to various reasons, some patients may be aggravated, and a few may be cancerous. Therefore, taking long-term gastroscopy follow-up is a necessary and effective measure.