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目的探讨住院患者使用第三代头孢菌素与医院获得性肺炎细菌谱的关系。方法回顾性分析2009年1月—2011年12月,某医院呼吸科169例呼吸道感染患者使用第三代头孢菌素一定时间后的细菌培养结果,观察其细菌谱的变化。结果检出的细菌大多对第三代头孢菌素类药耐药。结论第三代头孢菌素长时间的应用与医院获得性肺炎细菌谱的变化有一定的关系。
Objective To investigate the relationship between the use of third generation cephalosporins in hospitalized patients and the spectrum of hospital acquired pneumonia. Methods The bacterial culture results of 169 patients with respiratory tract infection in a hospital from January 2009 to December 2011 were analyzed retrospectively after using the third generation cephalosporins for a certain period of time. Results Most of the bacteria detected on the third generation cephalosporins resistant. Conclusion The long-term application of the third-generation cephalosporins has a certain relationship with the change of bacterial spectrum in hospital-acquired pneumonia.