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目的:探讨腹围与女性脑卒中高危人群颈动脉粥样硬化的相关性。方法:选取2012年5月至2013年2月在北京市丰台区王佐卫生服务中心、蒲黄榆社区卫生服务中心筛查的女性脑卒中高危人群1 228例,根据腹围是否大于等于80cm,将患者分为腹围正常组和腹围增大组进行颈动脉超声检查,观察2组患者颈动脉内膜中层厚度及斑块形成情况。结果:单因素分析示:与腹围正常组相比,腹围增大组颈动脉内膜增厚及斑块形成的发生率明显增高(P<0.01),颈动脉内膜增厚及斑块形成的发生率与腹围的增大呈正相关(Spearman相关系数分别为0.140、0.169)。多因素Logistic回归分析示:糖尿病病史、腹围增大、吸烟是导致颈动脉粥样硬化发生的危险因素,与颈动脉粥样硬化的发生相关。中医症状及证型分析:与腹围正常组相比,形体肥胖、口唇紫暗、头重如裹、口干等多个症状具有统计学意义(P<0.01或P<0.05);痰湿、血瘀两个证型在腹围增大组比例较大(P<0.05)。结论:在女性脑卒中高危人群中,腹围的增大。与颈动脉内膜增厚及斑块形成呈正相关,这部分人群更应该行颈动脉超声检查。与其他危险因素相比,腹围增大合并糖尿病史的女性出现颈动脉粥样硬化的可能性更大。腹围增大的人群更以易表现出痰湿、血瘀证型。
Objective: To investigate the relationship between abdominal circumference and carotid atherosclerosis in high-risk groups of stroke women. Methods: A total of 1 228 high risk groups of stroke patients were screened at Wangzuo Health Service Center and Puhuangyu Community Health Service Center in Fengtai District of Beijing from May 2012 to February 2013. According to whether the abdominal circumference is greater than or equal to 80cm, Carotid ultrasonography was performed for the normal abdominal and abdominal augmentation groups, and the carotid intima-media thickness and plaque formation in the two groups were observed. Results: Univariate analysis showed that carotid intima-media thickness and plaque formation in the abdominal circumference increased significantly (P <0.01), carotid intimal thickening and plaque The incidence of formation and abdominal circumference was positively correlated (Spearman correlation coefficients were 0.140,0.169). Multivariate Logistic regression analysis showed that diabetes mellitus and abdominal circumference increased and smoking was a risk factor for carotid atherosclerosis, which was related to the occurrence of carotid atherosclerosis. TCM Symptoms and Syndromes: Compared with the normal abdominal circumference group, body fat, dark purple lips, heavy head, such as wrapped, dry mouth and other symptoms were statistically significant (P <0.01 or P <0.05) The two syndromes of blood stasis had a larger proportion in abdominal enlargement group (P <0.05). CONCLUSION: Abdominal circumference is increased in women at high risk for stroke. And carotid artery intimal thickening and plaque formation was positively correlated, this part of the population should be more carotid artery ultrasound. Women with a history of increased abdominal circumference with diabetes mellitus were more likely to develop carotid atherosclerosis than other risk factors. Increased abdominal circumference of the crowd to more easily show phlegm, blood stasis type.