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用体外淋巴细胞对PHA的转化试验法,检测了81例宫颈癌病人和40例正常人的淋巴细胞转化率。发现淋巴细胞对PHA刺激转化的低反应者,宫颈癌病人比正常人显著增多。在正常人中占17.5肠,在宫颈癌病人中竟达58.0肠之多,并月_,淋巴细胞低反应的病人数,随着病情的发展而相应地增加。低反应者在O十I期宫颈癌病人中占2 4 .0%,在I期病人中占69.5%,而在皿期病人中占80.0%,表明机体淋巴细胞不断丧失反应性与肿瘤的发展有密切关系。此外,初步发现宫颈癌病人在用中草药获术及HeLa细胞疫苗治疗后,有一部分病例可恢复其淋巴细胞对PHA的反应性。但是,经上述治疗后,转化率仍低于正常值者,提示病情仍在发展。
In vitro lymphocyte PHA transformation assay, detecting 81 cases of cervical cancer patients and 40 cases of normal people’s lymphocyte transformation rate. Found that lymphocytes to PHA stimulation of the conversion of low responders, cervical cancer patients significantly increased than normal. Accounting for 17.5% of the normal population, as much as 58.0% of the colon cancer patients, and the number of patients with low response to lymphocytosis increased correspondingly with the progression of the disease. Low responders accounted for 24.0% of O patients with stage I cervical cancer, 69.5% of patients with stage I disease, and 80.0% of patients with stage III disease, indicating that the body’s lymphocytes continuously lose their reactivity and tumor development There is a close relationship. In addition, the initial discovery of cervical cancer patients with herbal medicine and HeLa cell vaccine treatment, there are some cases to restore their lymphocyte PHA reactivity. However, after the above treatment, the conversion rate is still below normal, suggesting that the disease is still developing.