论文部分内容阅读
目的:探讨喉巨细胞瘤的临床病理学特征及诊断、鉴别诊断要点。方法:报道1例喉巨细胞瘤,结合文献对其临床表现、影像学情况、病理形态学特点及鉴别诊断进行分析和探讨。结果:巨细胞瘤好发于长骨末端,约5%累及扁骨,不足5%的病例累及手足部的短管状骨,2%发生于头颈部。喉巨细胞瘤极罕见,发病平均年龄为42.4岁,男性多见。本例34岁,男性,左侧声门下3 cm×2 cm×2 cm肿块。镜下表现为圆形、卵圆形单核细胞及均匀分布其间的破骨细胞样巨细胞混合组成。结论:喉巨细胞瘤罕见,临床易误诊为恶性肿瘤,其病理学检查有特征性形态改变,结合影像学改变,可以确诊。
Objective: To investigate the clinicopathological features and diagnosis and differential diagnosis of laryngeal giant cell tumor. Methods: One case of laryngeal giant cell tumor was reported. The clinical manifestations, radiological features, pathomorphological features and differential diagnosis were analyzed and discussed in the literature. Results: Giant cell tumor occurs in the distal part of the long bones. About 5% involve the oblate bone. Less than 5% of the cases involve the short, tubular bones of the hand and foot, and 2% occur in the head and neck. Throat giant cell tumor is extremely rare, the average incidence of 42.4 years old, more common in men. In this case, 34 years old, male, 3 cm × 2 cm × 2 cm mass under the left supraglottic. Microscopic appearance of round, oval mononuclear cells and uniformly distributed between the osteoclast-like giant cells mixed composition. Conclusion: The rare laryngeal giant cell tumor of throat is easily misdiagnosed as a malignant tumor. Its pathological examination has characteristic morphological changes. Combined with the imaging changes, it can be diagnosed.