论文部分内容阅读
本文应用指示剂稀释技术观察了家兔ＳＭＡＰＯ休克时肺对￣（１２５）Ｉ标记的Ｐ物质（￣（１２５）－ＳＰ）和血管活性肠肽（￣（１２５）Ｉ－ＶＩＰ）的清除作用。结果表明，ＳＭＡＯ休克早期注入ＳＰ（ｌｐｍｏｌ／ｋｇ）一次流经肺循环的清除率（３５．０１±０．６４％）明显高于假手术对照组（２２．９６±２．２２％），Ｐ＜０．０１，注入ＶＩＰ（１．５ｐｍｏｌ／ｋｇ）一次流经肺循环的清除率（３７．８９±２．３０％），与假手术对照组（３８．５０±２２９％）相比无显著性差异。本实验结果证明家兔肺具有清除循环血中ＳＰ和ＶＩＰ的作用。休克时肺加强清除ＳＰ可能具有代偿意义。
In this paper, we observed the scavenging effect of lung on ~ (125) I labeled substance P (~ (125) -SP) and vasoactive intestinal peptide (~ (125) I-VIP) in rabbits SMAPO shock by using indicator dilution method. The results showed that the clearance rate of SMA (50.01 ± 0.64%) was significantly higher than that of the sham operation control group (22.96 ± 2.22%) at the first injection of SP (lpmol / kg) 0.01, VIP (1.5pmol / kg) once through the pulmonary circulation clearance rate (37.89 ± 2.30%), compared with the sham operation control group (38.50 ± 229%) no significant difference . The experimental results show that rabbit lung clearance of circulating blood SP and VIP role. Intensive lung clearance SP may play a compensatory role in shock.