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目的:探讨沙土鼠制作脑缺血模型的可能性、可靠性、重复性。方法:中断右颈总动脉血流,有42.3%出现了神经损伤的症状。动物在出现症状7小时后给予颈动脉放血处死,快速取脑,进行大体观察和病理学检查。结果:缺血侧大脑出现明确无误的缺血状态。结论:可利用沙土鼠制作理想的脑缺血模型。
Objective: To investigate the possibility, reliability and repeatability of gerbils in making cerebral ischemia model. Methods: The right common carotid artery was interrupted, and 42.3% of the patients had symptoms of nerve injury. The animals were sacrificed by carotid bleeding 7 hours after the onset of symptoms and brain was rapidly taken for general observation and pathological examination. Results: The ischemic brain showed an unambiguous state of ischemia. Conclusion: Gerbils can be used to make ideal cerebral ischemia model.