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目的 探讨铁负荷水平与Ⅱ型糖尿病的关系。方法 采用生化分析仪测定血清铁含量及血糖,采用化学发光法测定血清铁蛋白及胰岛素。结果 糖尿病患者铁储存水平显著增高(P<0.01),同时胰岛素抵抗指数值降低(P<0.01)。结论 铁储增高可能是造成胰岛素抵抗,导致Ⅱ型糖尿病的一个重要原因。
Objective To investigate the relationship between iron overload and type Ⅱ diabetes. Methods The serum iron and blood glucose were measured by biochemical analyzer. The serum ferritin and insulin were determined by chemiluminescence method. Results The level of iron in diabetic patients increased significantly (P <0.01), meanwhile, the index of insulin resistance decreased (P <0.01). Conclusion Increased iron stores may be caused by insulin resistance, leading to type Ⅱ diabetes is an important reason.