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丹参素——D(+)β(3,4-二羟基苯基)乳酸,经药理研究证实,其抗心肌缺血的疗效,在丹参水溶性成分中居于首位,并具有显著舒张离体猪冠状动脉的作用。丹参注射剂及复方丹参注射剂中含有多种水溶性成分,本文为适应丹参素的质量考察需要,建立了经纸层析分离,作紫外分光光度测定的方法,应用于产品分析,结果良好。丹参素层析分离与测定条件选择及方法步骤拟定如下。取注射剂,点样15μl于层析滤纸(28.5×4cm)上,置贮有展开剂用氯化钠饱和的1%醋酸层析缸中展开,待溶剂上升至前沿约25cm 处,取出晾干。以碱
Danshensu-D(+)β(3,4-dihydroxyphenyl)lactate has been proved by pharmacological research. Its anti-ischemic effect is the first in the water-soluble components of Salvia miltiorrhiza, and it has significant dilation of isolated pigs. The role of the coronary artery. Salvia miltiorrhiza injection and compound salvia miltiorrhiza injection contain many water-soluble components. This paper has established a paper-based chromatographic separation and UV spectrophotometry method for the quality inspection of Danshensu. It has been applied to product analysis and has a good result. Danshensu chromatographic separation and determination of the conditions for selection and method steps are formulated as follows. Take injections, spotting 15μl on chromatographic filter paper (28.5×4cm), storing the developing agent in a 1% acetic acid chromatography tank saturated with sodium chloride, and then starting the solvent to rise to the front of about 25cm, and taking it out to dry. Alkali