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An efficient and straightforward synthetic method has been developed for the preparation of 4-cyanofuran-3-carboxylate derivatives via iodine/potassium carbonate-promoted ring-opening/cyclization/rearrangement domino reaction of 1-cyanocyclopropane-1-carboxylates,which are a wide range of structurally interesting and pharmacologically significant compounds.
An efficient and straightforward synthetic method has been developed for the preparation of 4-cyanofuran-3-carboxylate derivatives via iodine / potassium carbonate-promoted ring-opening / cyclization / rearrangement domino reaction of 1-cyanocyclopropane-1-carboxylates, which are a wide range of structurally interesting and pharmacologically significant compounds.